Recombinant Human TP53 Regulated Inhibitor Of Apoptosis 1

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• Catalog number
  MBS145790
• Price:

  3220.79 USD

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• Size
  1 mg

# #

• Products_type
  Recombinant Protein
• Products_short_name
  [TP53 Regulated Inhibitor Of Apoptosis 1]
• Products_name_syn
  [TRIAP1 Human; TP53 Regulated Inhibitor Of Apoptosis 1 Human Recombinant; TP53 Regulated Inhibitor of Apoptosis 1; P53-Inducible Cell-Survival Factor; Mitochondrial Distribution And Morphology 35 Homolog; Protein 15E1.1; MDM35; WF-1; p53CSV; HSPC132]
• Other_names
  [TP53-regulated inhibitor of apoptosis 1; TP53-regulated inhibitor of apoptosis 1; TP53-regulated inhibitor of apoptosis 1; mitochondrial distribution and morphology 35 homolog; p53-inducible cell-survival factor; protein 15E1.1; TP53 regulated inhibitor of apoptosis 1; Protein 15E1.1; WF-1; p53-inducible cell-survival factor; p53CSV]
• Products_gene_name
  [TRIAP1]
• Other_gene_names
  [TRIAP1; TRIAP1; WF-1; MDM35; P53CSV; HSPC132; 15E1.1; p53CSV]
• Purity
  Greater than 90.0% as determined by SDS-PAGE.
• Form
  TRIAP1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 0.1M NaCl, 1mM DTT and 20% glycerol.Sterile Filtered clear solution.
• Storage_stability
  Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
• Description
  This 1 is suited for programmed cell-death studies. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

#

• Gene target
  TP53   Regulated   Inhibitor  
• Gene symbol
  TP53
• Short name
  Recombinant TP53 Regulated Inhibitor Of Apoptosis 1
• Technique
  Recombinant, apoptosis, apoptosis pathway, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E Coli
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens tumor protein p53 Regulated suppressor on programmed cellular destruction 1
• Alternative technique
  rec, celldeath
• Alternative to gene target
  tumor protein p53, BCC7 and LFS1 and P53 and TRP53, TP53 and IDBG-26364 and ENSG00000141510 and 7157, MDM2/MDM4 family protein binding, nuclei, Trp53 and IDBG-191036 and ENSMUSG00000059552 and 22059, TP53 and IDBG-635147 and ENSBTAG00000001069 and 281542

Gene info

• Identity
  HGNC:11998
• Gene
  TP53
• Long gene name
  tumor protein p53
• Synonyms
  • p53
  • LFS1
• Synonyms name
  • Li-Fraumeni syndrome
• GenBank acession
  • AF307851
• Locus
  17p13.1
• Discovery year
  1986-01-01
• Entrez gene record
  7157
• Pubmed identfication
  • 6396087
  • 3456488
  • 2047879
• RefSeq identity
  • NM_000546
• VEGA ID
  OTTHUMG00000162125
• Locus Specific Databases
  • IARC TP53 Mutation Database
  • p53 UMD TP53 mutation database
  • Database of Germline p53 Mutations
  • MUTP53LOAD, Mutant p53 Loss Of Activity Database
  • LRG_321

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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