Plasminogen Activator, Urokinase Receptor (uPAR) Polyclonal Antibody (Human), HRP

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• Catalog number
  PAA141Hu02-100ul-HRP
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• Size
  100ul

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• Description
  A Rabbit polyclonal antibody against Human Plasminogen Activator, Urokinase Receptor (uPAR). This antibody is labeled with HRP.
• Specifications
  Host: Rabbit; Species Reactivity: Human; Clonality: polyclonal; Tested applications: WB, IHC; Concentration: 500ug/ml; Isotype: IgG; Conjugation: HRP
• Additional_information
  Sequence of the immunogen: uPAR (Ser123~Cys216); Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
• Storage_and_shipping
  Upon receipt, store at -20°C or -80°C. Prepare working aliqotes prior to storage to avoid repeated freeze-thaw cycles.
• Notes
  Research Use Only.
• Properties
  If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Conjugation
  HRP Conjugated
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• Additional description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

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• Gene target
  Plasminogen   Activator   Urokinase   Receptor   uPAR  
• Gene symbol
  PLAUR
• Short name
  Plasminogen Activator, Urokinase Receptor (uPAR) Polyclonal Antibody ( ),
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  HRP
• Species
  Human, Humans
• Alternative name
  Plasminogen Activator, Urokinase Receptor (uPAR) polyclonal (antibody to-) (H. sapiens), horseradish peroxidase
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:9053
• Gene
  PLAUR
• Long gene name
  plasminogen activator, urokinase receptor
• Synonyms
  • URKR
  • UPAR
  • CD87
• Synonyms name
  • urokinase-type plasminogen activator (uPA) receptor
  • urokinase plasminogen activator surface receptor
• Locus
  19q13
• Discovery year
  1991-06-05
• Entrez gene record
  5329
• RefSeq identity
  • NM_002659
• Classification
  • LY6/PLAUR domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000182778
• Locus Specific Databases
  • LRG_637

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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